If you wish to disable ads on on some parts of the site, there are two options – per-post (or page) suppression and global suppression.

Per-post suppression

When editing a post or a page, toggle the “Don’t show ads on this post or page” setting in the sidebar to suppress ads on this post or page:

Global suppression

Visit the Advertising wizard of Newspack plugin to manage global suppression settings. Here, you can set ads to not be shown on some auto-generated pages (e.g. a particular category archive):